CHEM 3785 01: Biochemistry 1

CHEM 3785 - Biochemistry 1

Fall 2026 Syllabus, Section 01, CRN 40765,

Credit hours: 3

Course Meeting Times

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Instructor

Ganesaratnam Balendiran

Professional Qualifications:
PhD University of Wisconsin-Madison

Professor

Email: gkbalendiran@ysu.edu

Office: Office: Ward Beecher 6017 Phone: 1-330-941-7103

Office Phone: 7103

Additional Contact Methods:
Email and phone 1-330-941-7103

Preferred Contact Method: email: gkbalendiran@ysu.edu

Communication Expectations:
Communication Expectations: Avoid repeating information in email that is already discussed in the class.

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Course Description

3785. Biochemistry 1. Structure and function of proteins, nucleic acids, and carbohydrates. Includes techniques of protein purification and analysis, the study of enzyme catalysis and kinetics. Study of the organization and regulation of metabolic pathways: glycolysis, the citric acid cycle, and oxidative phosphorylation. Prereq.: "C" or better in CHEM 3720. 3 s.h.

Course Readings

Group Title Author ISBN
Optional Fundamentals of Biochemistry 6th edition Heilman and Woski, John Wiley & Sons, Inc., 2024

The course readings are subject to change in the event of extenuating circumstances, research developments, current events, and/or to ensure better learning.  

Additional Course Materials

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Course Learning Outcomes/Objectives/Goals

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How to Succeed in This Course

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Attendance Expectations

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Late Work Submission Policy

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Additional Course Expectations

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Artificial Intelligence Policy Statement

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Assignments/Assessments

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Grading and Grading Scale

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University Policies

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Schedule of Topics and Assignments

Day Date Proposed Topic Due/To Prepare for Class
Mon 8/24 Physical Properties of Water 2.1A,B,C,D
Wed 8/26 Hydrophobic Effect, Chemical Properties of Water 2.2A,B
Fri 8/28 Buffers 2.2C
Mon 8/31 Nucleotides, Nucleic Acid Structure 6.1A,B, 6.2A
Wed 9/2 Lipids 7.1A, 7.1E
Fri 9/4 Amino Acid Structure and Stereochemistry 3.1A-E, 3.3A,B
Wed 9/9 Peptide Bond Polypeptide Diversity, Genes Direct Protein Synthesis Protein Purification 3.2A, 3.4A,B 4 Introduction, 4.1A 6.4A,B Appendix A.1B , A.1C, A.1D
Fri 9/11 Quiz1
Mon 9/14 Protein Sequencing Appendix A.2A,B,C,D
Wed 9/16 Secondary Structure 4.1B,C
Fri 9/18 Tertiary Structure 4.2A,B,C
Mon 9/21 Quaternary Structure, Protein Stability Salting Out, Denaturation 4.3A,B, 4.4A,B A.1B
Wed 9/23 Myoglobin and Hemoglobin Cooperativity Box 4.6. page 108-119
Fri 9/25 Exam 1: Ch. 2, 3, 4, Appendix A (Exclude Myoglobin Hemoglobin), 6, 7
Mon 9/28 Allosteric Proteins, Abnormal Hemoglobin
Wed 9/30 Monosaccharides 5.1A
Fri 10/2 Glycosidic bonds, Polysaccharides 5.1B,C, 5.2A,C
Mon 10/5 Properties of Enzymes, Activation Energy 9.1A,B,C, 9.2A
Wed 10/7 Catalytic Mechanisms 9.2B, 9.2C, 9.3A Lysozyme: acid-base catalysis 9.3B-E,
Mon 10/12 Serine Proteases: covalent catalysis 9.4A,B,C, 9.5A,B,C
Wed 10/14 Enzyme Kinetics 10.1B
Fri 10/16 Exam 2: Ch. Box 4.6. page 108-119, 5, 9
Mon 10/19 Enzyme Inhibition 10.1C, 10.2A,B,C
Wed 10/21 Allosteric Regulation 10.3A
Fri 10/23 Free Energy Review 1.3C,D
Mon 10/26 Overview of Metabolism 12.1A,B
Wed 10/28 “High-Energy” Compounds 12.1C,D,E,
Fri 10/30 Coupled Reactions 12.2A,B,C,D
Mon 11/2 Oxidation-Reduction Reactions 12.3A,B,C
Wed 11/4 Reduction Potential and Free Energy Overview of Glycolysis 13.1, 13.2A
Rxns. of Glycolysis 13.2B-J
Mon 11/9 Fermentation, Control of Glycolysis 13.4A-C,13.6A Metabolism of Hexoses Other than Glucose 13.3A,B,C
Fri 11/13 Overview of the Citric Acid Cycle, Synthesis of acetyl-CoA 15.1, 15.2A,B
Mon 11/16 Exam 3: Ch. 10, 1, 12, 13
Wed 11/18 Reactions of the CAC 15.3A-H
Fri 11/20 Regulation of the CAC 15.4A,B,
Mon 11/23 Reactions Related to the CAC 15.5A,B
Mon 11/30 The Mitochondrion, Electron Transport 16.1A, 16.2A,B
Wed 12/2 Electron Transport 16.2C,D,E,F
Fri 12/4 Oxidative Phosphorylation 16.3A,B P/O Ratio, Uncoupling 16.1B,16.3C, Control of Oxidative Metabolism 16.4A,C
Mon 12/7 Comprehensive Final Exam: 10:30 – 12:30 p.m.

The course schedule, policies, procedures, and assignments in this course are subject to change in the event of extenuating circumstances, by mutual agreement, and/or to ensure better learning.