ENST 5830 - Toxicology and Risk Assessment
Fall 2026 Syllabus, Section 01, CRN 43543,
Credit hours: 3
Course Meeting Times
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Instructor
Felicia Armstrong
Email: fparmstrong@ysu.edu
Course Description
5830. Toxicology and Risk Assessment. A study of environmental toxicology of chemicals, primarily anthropogenic pollutants, and their effect on humans and ecosystems. Includes transportation of pollutants in the environment, biochemical reactions, toxicity testing methods, and dose-response assessment. Continues with an introduction in the process of estimating risk and the perception of those risks including how risk is used to set environmental standards. Prereq.: junior or senior with 9 semster hours in 3700 level or above in ENST, CHEM, BIOL, GEOL or CEEN. 3 s.h.
Course Readings
| Group | Title | Author | ISBN |
|---|---|---|---|
| Required | Calculated Risks, 2nd Edition | Joseph V. Rodricks | 978-0521783088 |
Calculated Risks: The Toxicity and Human Health Risk of Chemicals in our Environment, 2nd Edition by Joseph V. Rodricks, Cambridge University Press, 2006, ISBN 978-0521783088
The course readings are subject to change in the event of extenuating circumstances, research developments, current events, and/or to ensure better learning.
Assignments/Assessments
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Tentative Schedule of Topics and Assignments
| Day | Date | Reading(s) | Proposed Topic | Due/To Prepare for Class |
|---|---|---|---|---|
| Tue | 8/25 | Introduction to Risk Assessment | ||
| Thu | 8/27 | Chapter 1 | Chemical Review | |
| Tue | 9/1 | Chapter 2 | ADME | |
| Thu | 9/3 | Chapter 2 | ADME | Discussion 1 |
| Tue | 9/8 | Chapter 3 | Methods in toxicity testing | |
| Thu | 9/10 | Chapter 3 | Methods in toxicity testing | Discussion 2 |
| Tue | 9/15 | Chapter 3 | Toxicology: Dose-Response (RfD) | Chapter 3 |
| Thu | 9/17 | Chapter 4 | Reproductive Toxicology & Teratology and Other Toxic Effects | Quiz 1 |
| Tue | 9/22 | Chapter 5 & 6 | Carcinogens – SF | |
| Thu | 9/24 | Chapter 4 | Toxicology: Toxicokinetic, Site of Toxic Action | |
| Tue | 9/29 | Chapter 4 | Toxicology: Toxicokinetic, Site of Toxic Action | |
| Thu | 10/1 | Exam 1 | Exam | |
| Tue | 10/6 | Chapter 7 | Risk Assessment : Hazard ID | |
| Thu | 10/8 | Chemical Transport Models – Bioscreen | ||
| Tue | 10/13 | Bioscreen Review | Bioscreen Homwork Due | |
| Thu | 10/15 | Chemical Transport Models - J&E Model | ||
| Tue | 10/20 | J&E Model Review | J&E Model Homwork Due | |
| Thu | 10/22 | Chapter 8 & 9 | Risk Assessment: Dose-Response Assessment (IRIS Database), RfD, slope factors | |
| Tue | 10/27 | Exam 2 | IRIS Database Homework Due Exam 2 |
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| Thu | 10/29 | Chapter 7 & 8 | Risk Assessment : Exposure Assessment, Intake/CDI | |
| Tue | 11/3 | Chapter 8 & 9 | Risk Assessment : Risk Characterization Calculations: Risk, hazard quotient |
Quiz 2 CDI Homework Due |
| Thu | 11/5 | Chapter 8 & 9 | Calculations: Risk, hazard quotient Risk Assessment : Toxicity - Multiple Chemical Assessment |
HQ & Risk Homework Due |
| Tue | 11/10 | Overview of Ecological Risk Assessment Exam Review |
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| Thu | 11/12 | Exam 3 | Exam | |
| Tue | 11/17 | Final Project Introduction | ||
| Thu | 11/19 | Final Project Questions | ||
| Tue | 11/24 | Graduate Student Presentations | Graduate student papers due | |
| Thu | 11/26 | No Class, Holiday | ||
| Tue | 12/1 | Graduate Student Presentations | ||
| Thu | 12/3 | Final Project Meeting with Instructor | ||
| Tue | 12/8 | No class, Finals Week | ||
| Thu | 12/10 | No class, Finals Week | Final Project Presentations: Friday, 5:15-17:15 pm |
The course schedule, policies, procedures, and assignments in this course are subject to change in the event of extenuating circumstances, by mutual agreement, and/or to ensure better learning.