MLS 3704 - Clinical Immunology and Serology
Fall 2026 Syllabus, Section 01, CRN 42459,
Credit hours: 3
Course Meeting Times
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Instructor
Hiba Ismail
Email: hmismail@ysu.edu
Course Description
3704. Clinical Immunology and Serology . A study of the diagnostic applications of immunology and methods of serological testing. The immunology and diagnosis of infectious disease, autoimmunity, immunodeficiency, and immunoproliferative disease will be discussed. Coreq.: MLS 3704L. Cross-Listed: MLT 3704. 3 s.h.
Course Readings
| Group | Title | Author | ISBN |
|---|---|---|---|
| Required | Immunology and Serology in Laboratory Medicine by Mary Louise Turgeon 7th Edition. ISBN# 97803237119 |
The course readings are subject to change in the event of extenuating circumstances, research developments, current events, and/or to ensure better learning.
Assignments/Assessments
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Schedule of Topics and Assignments
| Day | Date | Reading(s) | Proposed Topic | Due/To Prepare for Class |
|---|---|---|---|---|
| Mon | 8/24 | Immunology serology lab Chapter 5 | Basic safety in immunology serology lab -Ch.# 5 | Safety Issues. Basic safety in immunology serology lab -Ch.# 5 |
| Wed | 8/26 | Lecture # 2: Overview of Immunology -Ch.# 1 | Lecture # 2: Overview of Immunology -Ch.# 1 | Lecture # 2: Overview of Immunology -Ch.# 1 |
| Mon | 8/31 | Lecture# 4: Soluble mediators of immune system- Ch.#2 | Lecture# 4: Soluble mediators of immune system- Ch.#2 | Lecture# 4: Soluble mediators of immune system- Ch.#2 |
| Wed | 9/2 | Lecture# 4: Soluble mediators of immune system- Ch.#2 | Lecture# 4: Soluble mediators of immune system- Ch.#2 | Lecture# 4: Soluble mediators of immune system- Ch.#2 |
| Mon | 9/7 | Lecture# 4: Soluble mediators of immune system- Ch.#2 | ||
| Wed | 9/9 | Quiz#1 (lecture 1, 2, 3)-Open 24 hours Lecture# 5-Cellular activities and Clinical Disorders of immune system Ch. #4 | Quiz#1 (lecture 1, 2, 3)-Open 24 hours Lecture# 5-Cellular activities and Clinical Disorders of immune system Ch. #4 | Quiz#1 (lecture 1, 2, 3)-Open 24 hours Lecture# 5-Cellular activities and Clinical Disorders of immune system Ch. #4 |
| Mon | 9/14 | Lecture# 6-Basic Serological Techniques–Ch. # 7 | Lecture# 6-Basic Serological Techniques–Ch. # 7 | Lecture# 6-Basic Serological Techniques–Ch. # 7 |
| Wed | 9/16 | Quiz #2 (lecture 4,5)-Open 24 hours Lecture# 7: Agglutination Methods and Electrophoresis Techniques Ch’s. # 8& 9 | Quiz #2 (lecture 4,5)-Open 24 hours Lecture# 7: Agglutination Methods and Electrophoresis Techniques Ch’s. # 8& 9 | Quiz #2 (lecture 4,5)-Open 24 hours Lecture# 7: Agglutination Methods and Electrophoresis Techniques Ch’s. # 8& 9 |
| Mon | 9/21 | Lecture# 8: Labeling Techniques in Immunoassay Ch# 10 Lecture #9 Flow Cytometry Ch. #11 Molecular Laboratory techniques Ch. #12 | Lecture# 8: Labeling Techniques in Immunoassay Ch# 10 Lecture #9 Flow Cytometry Ch. #11 Molecular Laboratory techniques Ch. #12 | Lecture# 8: Labeling Techniques in Immunoassay Ch# 10 Lecture #9 Flow Cytometry Ch. #11 Molecular Laboratory techniques Ch. #12 |
| Wed | 9/23 | Quiz#3 (lectures #6,7)-Open 24 hours Lecture #9: Flow Cytometry Ch. #11 Molecular Laboratory techniques Ch. #12 | Quiz#3 (lectures #6,7)-Open 24 hours Lecture #9: Flow Cytometry Ch. #11 Molecular Laboratory techniques Ch. #12 | Quiz#3 (lectures #6,7)-Open 24 hours Lecture #9: Flow Cytometry Ch. #11 Molecular Laboratory techniques Ch. #12 |
| Mon | 9/28 | Lecture #10: Infectious diseases: Overview and TORCH diseases Ch. #13 | Lecture #10: Infectious diseases: Overview and TORCH diseases Ch. #13 | Lecture #10: Infectious diseases: Overview and TORCH diseases Ch. #13 |
| Wed | 9/30 | Quiz #4 (lecture 8-9)-Open 24 hours Lecture #10: Infectious diseases: Overview and TORCH diseases Ch. #13 | Quiz #4 (lecture 8-9)-Open 24 hours Lecture #10: Infectious diseases: Overview and TORCH diseases Ch. #13 | |
| Mon | 10/5 | Lecture #11: Streptococcal Infections- Ch. #14 | Lecture #11: Streptococcal Infections- Ch. #14 | Lecture #11: Streptococcal Infections- Ch. #14 |
| Wed | 10/7 | Quiz #5 (lectures 10-11) Open 24 hours Lecture #12: Syphilis-Ch. #15 | Quiz #5 (lectures 10-11) Open 24 hours Lecture #12: Syphilis-Ch. #15 | Quiz #5 (lectures 10-11) Open 24 hours Lecture #12: Syphilis-Ch. #15 |
| Mon | 10/12 | Lecture #13-Vector born Disease- Ch. #16 | Lecture #13-Vector born Disease- Ch. #16 | Lecture #13-Vector born Disease- Ch. #16 |
| Wed | 10/14 | Lecture #13-Vector born Disease- Ch. #16 | Lecture #13-Vector born Disease- Ch. #16 | Lecture #13-Vector born Disease- Ch. #16 |
| Mon | 10/19 | Lecture #13-Vector born Disease- Ch. #16 | Lecture #13-Vector born Disease- Ch. #16 | Lecture #13-Vector born Disease- Ch. #16 |
| Wed | 10/21 | Lecture #15 Viral Hepatitis Ch. #18 | Lecture #15 Viral Hepatitis Ch. #18 | Lecture #15 Viral Hepatitis Ch. #18 |
| Mon | 10/26 | Lecture #15- Viral Hepatitis- Ch. #18 | Lecture #15- Viral Hepatitis- Ch. #18 | Lecture #15- Viral Hepatitis- Ch. #18 |
| Wed | 10/28 | Quiz #6 (lectures 14-15) Open 24 hours Lecture #16- Hypersensitivity reactions- Ch. #20 | Quiz #6 (lectures 14-15) Open 24 hours Lecture #16- Hypersensitivity reactions- Ch. #20 | Quiz #6 (lectures 14-15) Open 24 hours Lecture #16- Hypersensitivity reactions- Ch. #20 |
| Mon | 11/2 | Quiz #6 (lectures 14-15) Open 24 hours Lecture #16- Hypersensitivity reactions- Ch. #20 | Quiz #6 (lectures 14-15) Open 24 hours Lecture #16- Hypersensitivity reactions- Ch. #20 | Quiz #6 (lectures 14-15) Open 24 hours Lecture #16- Hypersensitivity reactions- Ch. #20 |
| Wed | 11/4 | Quiz #7 (Lectures 16-17) Open 24 hours Lecture# 18-Immunoproliferative Disorders. Ch.# 21 | Quiz #7 (Lectures 16-17) Open 24 hours Lecture# 18-Immunoproliferative Disorders. Ch.# 21 | Quiz #7 (Lectures 16-17) Open 24 hours Lecture# 18-Immunoproliferative Disorders. Ch.# 21 |
| Mon | 11/9 | Lecture# 19-Tolerance, autoimmunity, and autoimmune disorders Ch.- # 22 | Lecture# 19-Tolerance, autoimmunity, and autoimmune disorders Ch.- # 22 | Lecture# 19-Tolerance, autoimmunity, and autoimmune disorders Ch.- # 22 |
| Wed | 11/11 | University Closed | ||
| Mon | 11/16 | Lecture# 20 Systemic Lupus Erythematosus /ANA Ch. # 23 | Lecture# 20 Systemic Lupus Erythematosus /ANA Ch. # 23 | Lecture# 20 Systemic Lupus Erythematosus /ANA Ch. # 23 |
| Wed | 11/18 | Quiz # 8 Lecture 18-19 Open 24 hours Lecture #21-Rheumatoid Arthritis Ch. # 2 | Quiz # 8 Lecture 18-19 Open 24 hours Lecture #21-Rheumatoid Arthritis Ch. # 2 | Quiz # 8 Lecture 18-19 Open 24 hours Lecture #21-Rheumatoid Arthritis Ch. # 2 |
| Mon | 11/23 | Lecture# 22- Vaccines Ch.#27 | Lecture# 22- Vaccines Ch.#27 | Lecture# 22- Vaccines Ch.#27 |
| Wed | 11/25 | University Closed-Thanksgiving holiday | University Closed-Thanksgiving holiday | |
| Mon | 11/30 | Lecture # 23 -Transplantation and Tumor immunology Ch.# 25 | Lecture # 23 -Transplantation and Tumor immunology Ch.# 25 | Lecture # 23 -Transplantation and Tumor immunology Ch.# 25 |
| Wed | 12/2 | Quiz #9 (Lecture 20-21) Open 24 hours Lecture # 24-Tumor Immunology and Application of Massive Parallel Sequencing/ NGS Ch. - 26 | Quiz #9 (Lecture 20-21) Open 24 hours Lecture # 24-Tumor Immunology and Application of Massive Parallel Sequencing/ NGS Ch. - 26 | Quiz #9 (Lecture 20-21) Open 24 hours Lecture # 24-Tumor Immunology and Application of Massive Parallel Sequencing/ NGS Ch. - 26 |
| Wed | 12/9 | FINAL Exam Comprehensive |
The course schedule, policies, procedures, and assignments in this course are subject to change in the event of extenuating circumstances, by mutual agreement, and/or to ensure better learning.