CHEM 3785 01: Biochemistry 1

CHEM 3785 - Biochemistry 1

Summer 2026 Syllabus, Section 01, CRN 30488,

Credit hours: 3

Course Meeting Times

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Instructor

Dr. Michael Serra

Professional Qualifications:
Ph. D., Molecular, Cellular, and Developmental Biology, Iowa State University, Ames, IA
Bachelor of Science Biology, Bachelor of Arts Mathematics, Adrian College, Adrian, MI Office

Professor of Chemistry

Email: maserra@ysu.edu

Office: Ward Beecher, room 5033

Office Phone: (330)941-3667

Communication Expectations:
I review my e-mail several times a day so the best way to contact me is through my e-mail. I will respond within 24 hours during week days and within 48 hours during weekends.

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Course Description

3785. Biochemistry 1. Structure and function of proteins, nucleic acids, and carbohydrates. Includes techniques of protein purification and analysis, the study of enzyme catalysis and kinetics. Study of the organization and regulation of metabolic pathways: glycolysis, the citric acid cycle, and oxidative phosphorylation. Prereq.: "C" or better in CHEM 3720. 3 s.h.

Course Readings

Group Title Author ISBN
Required Fundamentals of Biochemistry 5th edition Voet, Voet, and Pratt

The course readings are subject to change in the event of extenuating circumstances, research developments, current events, and/or to ensure better learning.  

Additional Course Materials

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Course Learning Outcomes/Objectives/Goals

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How to Succeed in This Course

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Attendance Expectations

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Late Work Submission Policy

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Additional Course Expectations

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Artificial Intelligence Policy Statement

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Assignments/Assessments

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Grading and Grading Scale

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University Policies

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Schedule of Topics and Assignments

Day Date Reading(s) Proposed Topic Due/To Prepare for Class
Mon 6/29 2.1A,B 2.1C, 2.2A,B Physical Properties of Water Hydrophobic Effect, Chemical Properties of Water
Wed 7/1 2.2C, 3.1, 3.2A,B, 3.3A 3.3B, 4.1A,C,D,E Buffers Nucleotides, Nucleic Acid Structure Genes Direct Protein Synthesis Amino Acid Structure Online Quiz 1: Ch. 2 and 3.1 – 3.2A,B
Fri 7/3 University Holiday, no classes Independence Day (Happy 250th!)
Mon 7/6 4.1B, 4.2 5.1 6.1A 6.1B,D, 6.2B,C The Peptide Bond, Stereochemistry Polypeptide Diversity Peptide group Secondary and Tertiary Structure
Wed 7/8 6.3, 6.4A, 6.4B, 5.2B, 5.2C, 5.2D Quaternary Structure, Protein Stability, Denaturation, Salting Out, Chromatography, Electrophoresis Online Quiz 2: Ch. 4, 5.1, 6.1 and 6.2
Fri 7/10 5.3A,B,C 7.1A 7.1B,C,D Protein Sequencing, Myoglobin, Hemoglobin and Cooperativity
Mon 7/13 Exam 1: Ch. 2, 3, 4, 5.1 – 5.2C, 6
Wed 7/15 7.1D, 7.1E, 8.1A Hb: An Allosteric Protein, Sickle Cell Anemia, Monosaccharides
Fri 7/17 8.1B,C, 8.2A,C, 11.1A,B,C Glycosidic bonds, Polysaccharides, Properties of Enzymes Online Quiz 3: Ch. 5.2D, 5.3, 7
Mon 7/20 11.2, 11.3A-E 11.4A,B, 11.5A,B,C Transition State Theory, Catalytic Mechanisms, Lysozyme: acid-base catalysis, Serine Proteases: covalent catalysis
Wed 7/22 Exam 2: Ch. 5.2D-5.3C, 7, 8, 11
Fri 7/24 12.1B 12.1C, 12.2A, B, 12.3A Enzyme Kinetics: The Michaelis-Menten Eqn. Finding Vmax and KM, Enzyme Inhibition ATCase: An Allosteric Enzyme
Mon 7/27 1.3C,D, 14.1A,B, 14.1C,D,E, 14.2A Free Energy Review, Overview of Metabolism, ATP Online Quiz 4: Ch. 1 and Ch. 12
Wed 7/29 14.2B,C,D, 14.3A, B, C, 15.1, 15.2A Coupled Rxns., Other “High-Energy” Cmpds., Reduction Potential and Free Energy, Overview of Glycolysis, Rxns. of Glycolysis
Fri 7/31 15.2B-J, 15.3A-C, 15.4A, 15.5A,B,C Reactions of Glycolysis, Fermentation, Control of Glycolysis, Metabolism of Hexoses Other than Glucose Online Quiz 5: Ch. 14, Ch. 15.1 and 15.2
Mon 8/3 17.1, 17.2A,B 17.3A-H 17.4A,B, 17.5A,B Overview of the Citric Acid Cycle, Synthesis of acetyl-CoA, Rxns. of the CAC, Regulation of the CAC, Rxns. Related to the CAC
Wed 8/5 Exam 3: Ch. 1, 12, 14, 15
Fri 8/7 18.1A, 18.2A,B 18.2C,D,E,F 18.3A,B,C,D The Mitochondrion, Electron Transport Electron Transport, Chemiosmotic theory, ATP synthase, P/O ratio, Uncoupling agents
Mon 8/10 18.4A,B Control of Oxidative Metabolism Online Quiz 6: Ch. 17
Wed 8/12 Review
Fri 8/14 Comprehensive Final Exam

The course schedule, policies, procedures, and assignments in this course are subject to change in the event of extenuating circumstances, by mutual agreement, and/or to ensure better learning.